Contents: Introduction. 1. Bioinformatics and next generation sequencing. 2. Adverse effect of transgenics through pollination or gene flow. 3. Modern molecular techniques for new innovation. 4. Effect of replacement of fish meal by broiler by-products meal in rearing stage of genetically improved farmed tilapia (gift) diet. 5. RNA binding and inhibition of function by metal complexes. 6. Characterization, assessment of genetic diversity, screening for protein content and bruchid infestation in cowpea. 7. Bioinformatics tools in microbial biotechnology. 8. Tools for recombinant antibody production.