This book covers most of the topics with latest information on bone in general and research on bone healing in particular. The book is divided into 27 chapters covering almost all aspect of orthopaedic research in small and lab animals including basic knowledge about bone; fracture types and fracture healing; bone grafts and bone substitute; internal fracture fixation; external fracture fixation; bone morphogenetic protein; transforming growth factors; role of mesenchymal stem cell in osteoinduction; fracture healing in critical sized bone defect and in very large bone defect, effect of herb and herbal product in fracture healing, role of different hormones, anabolic steroid, NSAID drug, bone wax, ultrasound in fracture healing; minimal invasive fracture repair; management of comminuted femoral and tibial metaphyseal fracture; endocrine role of fracture healing; evaluation of bone graft, ceramic biomaterials in fracture healing and physiotherapy of orthopedic patients. This book includes different research findings on application of herb, herbal product, bone graft, ceramic biomaterials, mesenchymal stem cells, and different osteoinducers in bone regeneration. The main objective of this book is to provide the latest information to meet the requirements of not only undergraduate and post graduates research scholars but also to the teachers, biologists and clinician involved in animal treatment and orthopaedic research.