Education is the light of life. It is the right to have quality education to everybody whereas education to the disabled through inclusive education has several setbacks and challenges. Inclusive education is an approach to combining in school environments with special education and general education students to promote diversity, lifelong learning, and create a more equitable society. The practice of inclusive education receives an increasing number of strong in improvements additional support and interest in education system in almost all countries in the world. This book highlights on the practices and challenges of inclusive education in primary schools and focused on the present status of implementation of inclusive education and the roles of local government and also the main challenges being faced to implement inclusive education, and initiatives taken. This research study was conducted at Gambella Town, Ethiopia. This book has emphasized on identification of challenging factor like physical factors, sociocultural factors, economic factors and personal factors which are the main obstacles for the implementation of inclusive education. This book explains that how to create a healthy and qualitative environment for better implementation of inclusive education and suggests remedies to overcome such problems. Definitely this book is useful and helpful to all those who are working in inclusive education field and also to the concerned departments of education.