This book gives the information about synthesis of phosphonates via Michaelis-Arbuzov reaction. Synthesis of organic compounds through microwave method is an ideal method for rapid reaction scouting and optimization of reaction conditions. Solvent free conditions and ionic liquid promoted synthesis are best methods in green chemistry which are highlighted in this book. The synthesis and reaction mechanism are illustrated with in detailed examples. The recent literature has been reviewed with new examples to demonstrate reactions with better explanation.