Contents: 1. Introduction. 2. Origin of Science. 3. Big Bang Theory. 4. Origin and Evolution of Life. 5. Origin of Religion. 6. Existence of God. 7. God and Nature. 8. Spirituality. 9. Mysticism. 10. Conclusion: The Interface of Science and Spirituality. 11. Bibliography. Index. Science and spirituality converge to one point and also diverge from the same. There is a strong relationship between the both, like two distinct intersecting circles with a large shared portion, as also independent identities. The diversity of living beings with graded degree of complexities is amazing. A mind ripe enough, admires the intricacies of life sprouting a perennial zeal to uncover the mystery of the organizing principle: God or Nature. The book will take the reader on a voyage starting from the origin of universe through the origin of life to the confluence of science and spirituality.