Contents: 1. Topical Antifungals and Classes of Topical Antifungal. 2. Drugs—An Overview/Surabhi Sinha, Sidharth Tandon and Rashmi Sarkar. 3. Dermatophytoses—What is New?/Sheetanshu Kumar and Vinay Keshavamurthy. 4. Other Cutaneous Superficial Fungal Infections and their Topical Treatment/Nisha V Parmar and Rashmi Sarkar. 5. Onychomycoses—Latest Developments andTopical Treatment/Somodyuti Chandra and Indrashis Podder. 6. Topical Polyenes/Mala Bhalla and Monika. 7. Allylamine and Benzylamine Topical Antifungals/Nisha V Parmar and Rashmi Sarkar. 8. Topical Azole Antifungals/Mala Bhalla and Priyanka Sharma. 9. Hydroxypyridone Topical Antifungal/Sneha Ghunawat. 10. Antifungal Resistance: What We Know/Surabhi Sinha and Rashmi Sarkar. 11. Topical Azole Antifungals/Mala Bhalla and Priyanka Sharma. 12. Hydroxypyridone Topical Antifungal/Sneha Ghunawat. 13. Antifungal Resistance: What We Know/Surabhi Sinhaand Rashmi Sarkar. World clinics are periodicals of evidence-based reviews proposed as a source of comprehensive, state-of-the-art reviews written by experts. Each issue of “World Clinics Dermatology” would focus on a single theme covering topics that are relevant to clinical understanding and decision-making. Each topic would be developed to reflect the current evidence, research, existing guidelines and recommendations as well the clinical experience of experts. The current issue of World Clinics in Dermatology 2019 gives a wide insight into older and newer exciting broad-spectrum topical antifungals.